Novel approaches and technical advances of locally advanced cervical cancer

Node positive locally advanced cervical cancer continues to have poor outcomes and constitutes a medical unmet need. Cervical cancer treatments incorporate systemic therapy with the backbone of radiation therapy techniques. We will review the optimal strategy for systemic therapy, and novel agents including immunotherapy. Clinical trials will also be reviewed.

Jyoti Mayadev

University of California
Medical Director of Gynaecologic Brachytherapy

Dr. Mayadev is the medical director of gynecologic brachytherapy and chief of the gynecologic malignancy disease team in the division of clinical and translational research at the University of California. She oversees the clinical focus and translational research aspect of image guided brachytherapy for gynecologic cancers. She is also a member of the breast cancer disease team.

Dr. Mayadev is a widely recognized national leader in the field of gynecologic radiation therapy and image guided brachytherapy for gynecology oncology. She is co-chair of the national NRG oncology cooperative group phase I/developmental therapeutics committee, and a core member of the cervical cancer committee. She participates in the strategy and key design elements of cervical cancer national trials for the execution of new treatment paradigms and analysis for gynecology oncology patients. Furthermore, she is the national principal investigator on phase I clinical trials in cervical cancer exploring the use of immunotherapy in patients with locally advanced cervical cancer. She is widely published, and received grant funding including Varian Medical Systems and Koman for the Cure.

Prior to her arrival at UC San Diego, Dr. Mayadev was the director of brachytherapy at UC Davis, where she initiated their image guided brachytherapy programs, and lead the gynecologic and breast oncology research programs in radiation oncology. She has received awards for her teaching and clinical expertise, including “Educator of the Year,” and the “Dean’s Award for Gynecologic Interstitial Brachytherapy”. Dr. Mayadev is a consistently invited speaker at the American Society of Therapeutic Radiation Oncology (ASTRO) national conference, and the American Brachytherapy Society (ABS) to further knowledge and research in radiation oncology. Dr. Mayadev conceived, designed and developed the “Image Guided Brachytherapy Handbook”, and served as the Editor-in-Chief, published by Springer.